https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 The relationship between white matter microstructure and general cognitive ability in patients with schizophrenia and healthy participants in the ENIGMA consortium https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40457 Wed 27 Jul 2022 11:14:03 AEST ]]> The genetic architecture of the human cerebral cortex https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42676 Wed 22 Mar 2023 14:34:07 AEDT ]]> Virtual Ontogeny of Cortical Growth Preceding Mental Illness https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51029 Wed 16 Aug 2023 10:09:44 AEST ]]> Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44630 Tue 18 Oct 2022 12:11:18 AEDT ]]> Beyond the global brain differences: intra-individual bariability differences in 1q21.1 distal and 15q11.2 BP1-BP2 deletion carriers https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54564 Tue 14 May 2024 13:54:22 AEST ]]> Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) consortium https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33388 Tue 03 Sep 2019 17:54:11 AEST ]]> Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47202 Thu 15 Dec 2022 11:18:18 AEDT ]]> The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42338 N = 29,125 cases and 34,836 controls), a robust polygenic signal was observed from gene sets based on TCF4, FMR1, upregulation from MIR137 and downregulation from CHD8. Additional analyses revealed a constant floor effect in the amount of variance explained, consistent with the omnigenic model. Thus, we report that putative core gene sets showed a significant effect above and beyond the floor effect that might be linked with the underlying omnigenic background. In addition, we demonstrate a method to quantify the contribution of specific gene sets within the omnigenic context.]]> Mon 22 Aug 2022 14:00:20 AEST ]]> Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50977 Mon 14 Aug 2023 15:24:38 AEST ]]> Age at first birth in women is genetically associated with increased risk of schizophrenia https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43035 Mon 12 Sep 2022 11:49:25 AEST ]]> Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51931 1.5 SD) in SA, 118 (7.47%) in CT and 161 (10.20%) in SV. Psychosis transition was not significantly associated with any measure of heterogeneity. Overall, our examination of neuroanatomical heterogeneity within the CHR-P state indicated greater divergence in neuroanatomical profiles at an individual level, irrespective of psychosis conversion. Further large-scale investigations are required of those who demonstrate marked deviation.]]> Fri 22 Sep 2023 11:07:30 AEST ]]>